Now Accepting Pilot Physicians

AI Clinical Decision Support, Built for Complex Diagnosis

GENA 3.0 is an AI clinical decision support system for doctors. It analyzes patient symptoms, builds an evidence-based differential, and helps clinicians consider complex, genetic, and rare conditions earlier in the workup — bridging advanced AI and everyday clinical practice.

Diagnosis is harder than ever, and the stakes are high

Research published in BMJ Quality & Safety estimates that roughly 800,000 people in the U.S. experience serious harm each year linked to diagnostic error.¹ With more than 25,000 recognized diseases, no clinician can hold every possibility in mind during a brief, high-volume visit.

Getting to the right answer sooner can mean avoiding tens of thousands, and in the most complex cases, far more, in downstream testing, referrals, and delayed care.²

This is where AI for medicine can help: not by deciding, but by widening the view. GENA 3.0 brings medical-diagnosis AI to the point of care as a second layer of reasoning the clinician stays in control of.

How It Works

GENA PLM is being built with privacy, security, and compliance at its core. From synthetic data generation to strict data governance, every element of the model prioritizes patient safety, trust, and ethical AI.

Evidence-based diagnoses in four steps

1

Describe the Case

Enter symptoms and findings in plain language, by voice or text, before or during the visit.

Confirm the Terms

GENA adapts to you, translating your clinical inputs into standard medical terminology with every step open to edit or override.

2

3

Review the Differential Diagnoses

A deterministic reasoning engine returns a scored, iterable differential, ranked and ready to refine.

Act on the Evidence

Explore the details that matter like suspected conditions, genetic possibilities, relevant tests, drug information, and specialist referrals, then export a structured summary for the chart and back office.

4

5

Track Case Progress

GENA Screen provides real-time updates, tracking each stage of the testing journey from kit dispatch to lab processing, so clinicians stay informed every step of the way.

THE PILOT

Help shape the standard of care

We're inviting a select group of clinician practices to run GENA 3.0 on real complex cases ahead of launch, and to tell us what works.

What you get

  • Early, full access at no cost to you

  • A direct line to shape the product roadmap

  • Hands-on onboarding and dedicated support

  • Publication opportunities

What we ask

  • Run a handful of your real complex cases

  • Share brief, structured feedback along the way

  • About two minutes of feedback after each case you run

Frequently Asked Questions About AI Clinicial Decision Support

What is GENA 3.0?

GENA 3.0 is an AI clinical decision support system that helps doctors build evidence-based differential diagnoses for complex, genetic, and rare cases. It analyzes patient symptoms and surfaces ranked, traceable possibilities the clinician reviews and decides on. We've iteratively realeased GENA, with the first version being a geneticists' platform for faster genomic analysis, and the second iteration being a symptoms to genomic disease checker. GENA 3.0 combines all we've learned into a diagnostic tool that blends intelligence and diagnostics together.

Is GENA 3.0 a diagnostic device?

No. GENA 3.0 provides clinical decision support. It is designed to assist a qualified clinician's reasoning, not to provide a diagnosis or treatment decision on its own. All clinical decisions remain with the treating provider.d an image, select any Frame, and either double-click on it, or go to the Fill property. In the Fill property, switch to the image icon. Here, you can upload images.

How is this different from general-purpose AI for medicine?

GENA 3.0 uses a deterministic reasoning engine grounded in curated medical sources rather than open-ended generative text. Results are traceable to their source and reproducible, which is what sets purpose-built medical-diagnosis AI apart from a general chatbot.

Who is GENA 3.0 for?

Outpatient clinicians, primary care providers, geneticists, and genetic counselors — anyone who manages complex, genetic, or difficult diagnses.

What is GENA 3.0?

GENA 3.0 is an AI clinical decision support system that helps doctors build evidence-based differential diagnoses for complex, genetic, and rare cases. It analyzes patient symptoms and surfaces ranked, traceable possibilities the clinician reviews and decides on. We've iteratively realeased GENA, with the first version being a geneticists' platform for faster genomic analysis, and the second iteration being a symptoms to genomic disease checker. GENA 3.0 combines all we've learned into a diagnostic tool that blends intelligence and diagnostics together.

Is GENA 3.0 a diagnostic device?

No. GENA 3.0 provides clinical decision support. It is designed to assist a qualified clinician's reasoning, not to provide a diagnosis or treatment decision on its own. All clinical decisions remain with the treating provider.

How is this different from general-purpose AI for medicine

GENA 3.0 uses a deterministic reasoning engine grounded in curated medical sources rather than open-ended generative text. Results are traceable to their source and reproducible, which is what sets purpose-built medical-diagnosis AI apart from a general chatbot.

Who is GENA 3.0 for?

Outpatient clinicians, primary care providers, geneticists, and genetic counselors — anyone who manages complex, genetic, or difficult diagnses.

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Subscribe to stay updated on how GENA is shaping the future of AI in healthcare.